Post about endometriosis and immunity
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Endometriosis and Immunity

Endometriosis: What is it exactly?

Endometriosis is a condition where cells of the endometrium, the tissue lining the inside of the uterus that is shed during menstruation, invade other tissues within the abdominal cavity (ovaries, fallopian tubes, bladder, cervix or rectum).

These “misplaced” endometrial cells also react to the increase in oestrogen and progesterone, causing bleeding and pain a few days before and after the period. Women suffering from endometriosis suffer from very painful periods, as well as digestive disorders, fatigue, pain during sexual intercourse, difficulty becoming pregnant or even infertility. 

It is assumed that endometriosis is caused by multiple environmental and genetic factors. However, its exact origin is still unclear. According to the most extended theory, endometrial cells are released during the menstrual cycle and settle in the pelvic peritoneum, where they grow under hormonal influence. However, this is only possible if the immune response is impaired, since a properly functioning immune system should prevent anomalous cell growth. 

Is endometriosis an immunological disease?

Inflammation is among the immunological conditions associated with endometriosis. Increased production of antibodies related with autoimmunity has also been observed. Given that hormones play an important role in the disease, an imbalance of the psycho-neuroendocrine-immune axis might be involved too. 

These immune alterations frequently cause patients to develop autoimmune or chronic diseases: 

  • Thyroid gland disorders
  • Fibromyalgia
  • Multiple sclerosis
  • Allergies
  • Asthma

Micro-immunotherapy & Endometriosis

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Micro-immunotherapy sends sequential information to the immune system through immune messenger substances in low doses (i.e. gently and sustainably, as these substances circulate in very low concentrations inside the body), thus speaking the same language.

 Through a specific, targeted and sequential administration of cytokines and other immune messenger substances, in endometriosis micro-immunotherapy contributes to dampening the underlying inflammatory mechanisms and controlling antibody production while bringing the psycho-neuroendocrine-immune axis back in sync. Thereby, it favours the improvement of symptoms and helps prevent the onset of associated autoimmune and chronic diseases.

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  1. Salomón Kuri, J. Solano Sánchez, S.R., Maldonado Miranda, E.P. Inmunología de la endometriosis. Anales Médicos. 2013, 58 (3):180-186
  2. Pasqualini, S. Endometriosis, la enfermedad autoinmune del Siglo XXI. Télam. Accesible a través de: []
  3. Amatriain, M. Endometriosis: ¿es posible recurrir a la microinmunoterapia?. Newsletter AEMI (2018).