Fields of application

Bone remodeling and micro-immunotherapy

We have 206 bones beneath our skin. Together, they make up the structure that holds us upright. Their function is mechanical, they allow us to move. But not only, since they also play a protective, synthetic and metabolic role. The protective role is quite obvious: one need only think about the skull “quartering” the brain or the rips covering the lungs and the heart. The synthetic function refers to the production of red and white blood cells in the bone marrow, i.e. the site of immune cell production. And last but not least, bones play their part in metabolism: they are the place where minerals, fat and growth factors are stored, they help keep the acid-base balance of the body by storing and releasing alkaline salts, and reduce circulating sugar and fat through osteocalcin production, which stimulates insulin production.

Is there any further relationship between the bone system and the immune system apart from the former being the side of production of the cells of the latter? As a matter of fact, these two systems partly use the same messenger substances: cytokines. The regulation of bone remodeling depends to a great extent on the action of cytokines on osteoblasts (cells that favour bone formation) and osteoclasts (cells favouring bone destruction).

In case of bone disease, like osteoporosis/osteopenia, periodontal disease or bone fractures, micro-immunotherapy has a special formula aimed at curbing osteoclast maturation, stimulating the osteoblast pathway and mineralisation of the matrix as well as reducing the inflammatory process and the pain.

Micro-immunotherapy helps to gently rebalance bone turnover to maintain or recover healthy and strong bones.

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